Overview

  • Dr. Shollenberger is an interdisciplinary and collaborative researcher focused on improving human health and mentoring the next generation of scientists.
  • Selected Publications

    Articles In Academic Journals

    Year Title
    2015 Schistosoma mansoni Soluble Egg Antigens Enhance T Cell Responses to a Newly Identified HIV-1 Gag H-2(b) EpitopeClinical and Vaccine Immunology. 193-199.
    2015 Vaccine Self-Assembling Immune Matrix Is a New Delivery Platform That Enhances Immune Responses to Recombinant HBsAg in MiceClinical and Vaccine Immunology. 336-343.
    2014 Schistosoma mansoni Soluble Egg Antigens Enhance Listeria monocytogenes Vector HIV-1 Vaccine Induction of Cytotoxic T CellsClinical and Vaccine Immunology. 1232-1239.
    2013 HIV-1 vaccine-specific responses induced by Listeria vector vaccines are maintained in mice subsequently infected with a model helminth parasite, Schistosoma mansoniVaccine. 5651-5658.
    2013 Successful vaccination of immune suppressed recipients using Listeria vector HIV-1 vaccines in helminth infected miceVaccine. 2050-2056.
    2007 Mechanism of naked DNA clearance after intravenous injectionThe Journal of Gene Medicine. 613-619.
    2007 Novel nonviral vectors target cellular signaling pathways: Regulated gene expression and reduced toxicityJournal of Pharmacology and Experimental Therapeutics. 777-783.
    2007 Sine-wave current for efficient and safe in vivo gene transferMolecular Therapy. 1842-1847.
    2006 Mechanism of in vivo DNA transport into cells by electroporation: electrophoresis across the plasma membrane may not be involvedThe Journal of Gene Medicine. 353-361.
    2004 Enumeration, Resuscitation, and Infectivity of the Sublethally Injured Erwinia Cells Induced by Mild Acid TreatmentPhytopathology. 76-81.
    2004 Non-immunostimulatory nonviral vectorsThe FASEB Journal. 1779-1781.
    2003 Lethal and Sublethal Action of Acetic Acid on Salmonella In Vitro and on Cut Surfaces of Apple SlicesJournal of Food Science. 2793-2798.
    Novel Nonviral Vectors Target Cellular Signaling Pathways: Regulated Gene Expression and Reduced ToxicityJournal of Pharmacology and Experimental Therapeutics. 777-783.

    Chapters

    Year Title
    2006 Liposome-Polycation-DNALiposome Technology, Volume II. Abingdon, Oxon: Informa Healthcare.

    Conference Papers

    Year Title
    2017 An egg protein from Schistosoma mansoni is promising for development of high-specificity diagnostics in the era of intensified control.  384-384.
    2017 LNFPIII-Dex conjugates function in vivo to normalize metabolic function in High-Fat Diet Obese mice.  1190-1191.
    2017 Vaccine self-assembling immune matrix is a non-viral delivery platform that improves overall vaccine performance while maintaining safety and stability
    2015 Enhancing immunogenicity of recombinant protein vaccines in mice with vaccine self-assembling immune matrix, a non-viral delivery platform
    2014 VacSIM (TM) - a new delivery method increases influenza vaccine efficacy
    2014 Vaccine self-assembling immune matrix (VacSIM) is a non-viral delivery platform that augments responses to recombinant protein vaccines
    2006 Interaction of LPD Nanoparticles with Dendritic Cells.  S412-S412.
    2006 Mechanism of Naked DNA Clearance after Intravenous Injection.  S412-S413.

    Research Overview

  • The long term goal of my research program is to produce more effective vaccines, specifically designed with target populations in mind, by understanding the mechanisms of vaccine efficacy in the context of confounding factors. The objectives of my research program will be to improve vaccine efficacy for high-risk and immune-suppressed populations, such as the elderly and helminth-infected, by (1) interrogating the host-parasite-vaccine tripartite relationship, (2) understanding the contribution of the microbiome to vaccine efficacy, and (3) modifying delivery of vaccines and the way in which vaccines interact with the immune system.
  • Expertise Keywords

  • Biology : immunology, vaccinology, parasitology, infectious diseases, microbiology, drug and gene delivery, nanotechnology
  • Education And Training

  • Ph.D. in Biochemistry & Molecular Genetics, University of Pittsburgh 2009
  • Full Name

  • Lisa Shollenberger