Overview

  • I completed high school in Athens, Greece and BS, MS and PhD degrees in Pharmacology in the US. After post-doctoral studies at Yale, I spend the next 32 years at the Medical College of Georgia where I founded the Vascular Biology Center. I moved to ODU in 2013. I am married to Dr. Chrstiana Dimitropoulou and have two daughters.
  • Selected Publications

    Articles In Academic Journals

    Year Title
    2018 Targeting ovarian cancer and endothelium with an allosteric PTP4A3 phosphatase inhibitorOncotarget. 8223-8240.
    2017 Hydrocortisone and ascorbic acid synergistically prevent and repair lipopolysaccharide-induced pulmonary endothelial barrier dysfunctionChest. 954-962.
    2017 Hyper-activation of pp60(Src) limits nitric oxide signaling by increasing asymmetric dimethylarginine levels during acute lung injuryFree Radical Biology & Medicine. 217-228.
    2017 LPS induced acute lung injury involves the NF-?B-mediated downregulation of Sox18American Journal of Respiratory Cell and Molecular Biology.
    2017 ResponseChest. 451-452.
    2015 Histone deacetylase inhibitors prevent pulmonary endothelial hyperpermeability and acute lung injury by regulating heat shock protein 90 function.American journal of physiology. Lung cellular and molecular physiology. L1410-9.
    2015 p53 protects against LPS-induced lung endothelial barrier dysfunction.American journal of physiology. Lung cellular and molecular physiology. L776-87.
    2014 Commentary: CHIPping away pancreatic tumors?Annals of translational medicine. 105.
    2014 Dimethylarginine dimethylaminohydrolase II overexpression attenuates LPS-mediated lung leak in acute lung injury.American Journal of Respiratory Cell and Molecular Biology. 614-25.
    2014 Heat shock protein 90 inhibitors prevent LPS-induced endothelial barrier dysfunction by disrupting RhoA signaling.American Journal of Respiratory Cell and Molecular Biology. 170-9.
    2014 Lipopolysaccharide-induced lung injury involves the nitration-mediated activation of RhoA.The Journal of biological chemistry. 4710-22.
    2014 NADPH oxidase 4 is expressed in pulmonary artery adventitia and contributes to hypertensive vascular remodeling.Arteriosclerosis, thrombosis, and vascular biology. 1704-15.
    2014 Novel mechanism of attenuation of LPS-induced NF-?B activation by the heat shock protein 90 inhibitor, 17-N-allylamino-17-demethoxygeldanamycin, in human lung microvascular endothelial cells.American Journal of Respiratory Cell and Molecular Biology. 942-52.
    2013 LPS induces pp60c-src-mediated tyrosine phosphorylation of Hsp90 in lung vascular endothelial cells and mouse lung.American journal of physiology. Lung cellular and molecular physiology. L883-93.
    2012 Hsp90 regulates O-linked ?-N-acetylglucosamine transferase: a novel mechanism of modulation of protein O-linked ?-N-acetylglucosamine modification in endothelial cells.American journal of physiology. Cell physiology. C1786-96.
    2012 Opposing actions of heat shock protein 90 and 70 regulate nicotinamide adenine dinucleotide phosphate oxidase stability and reactive oxygen species production.Arteriosclerosis, thrombosis, and vascular biology. 2989-99.
    2012 Protein kinase C-? and arginase I mediate pneumolysin-induced pulmonary endothelial hyperpermeability.American Journal of Respiratory Cell and Molecular Biology. 445-53.
    2012 Regulation of asthmatic airway relaxation by estrogen and heat shock protein 90.Journal of cellular physiology. 3036-43.
    2012 Regulation of endothelial barrier function by TGF-? type I receptor ALK5: potential role of contractile mechanisms and heat shock protein 90.Journal of cellular physiology. 759-71.
    2011 ?V?3 integrin regulates macrophage inflammatory responses via PI3 kinase/Akt-dependent NF-?B activation.Journal of cellular physiology. 469-76.
    2011 C-terminus of heat shock protein 70-interacting protein-dependent GTP cyclohydrolase I degradation in lambs with increased pulmonary blood flow.American Journal of Respiratory Cell and Molecular Biology. 163-71.
    2011 Hsp90 regulates NADPH oxidase activity and is necessary for superoxide but not hydrogen peroxide production.Antioxidants & redox signaling. 2107-19.
    2010 Harvesting, identification and barrier function of human lung microvascular endothelial cells.Vascular pharmacology. 175-81.
    2010 Mechanisms of nitric oxide synthase uncoupling in endotoxin-induced acute lung injury: role of asymmetric dimethylarginine.Vascular pharmacology. 182-90.
    2010 The lectin-like domain of TNF protects from listeriolysin-induced hyperpermeability in human pulmonary microvascular endothelial cells - a crucial role for protein kinase C-alpha inhibition.Vascular pharmacology. 207-13.
    2009 Effect of PPARgamma inhibition on pulmonary endothelial cell gene expression: gene profiling in pulmonary hypertension.Physiological genomics. 48-60.
    2009 Estrogen replacement therapy prevents airway dysfunction in a murine model of allergen-induced asthma.Lung. 116-27.
    2009 Regulators of endothelial and epithelial barrier integrity and function in acute lung injury.Biochemical pharmacology. 1763-72.
    2008 Endothelial nitric oxide (NO) and its pathophysiologic regulation.Vascular pharmacology. 134-40.
    2008 Endothelial pathomechanisms in acute lung injury.Vascular pharmacology. 119-33.
    2008 Heat shock protein 90 inhibitors attenuate LPS-induced endothelial hyperpermeability.American journal of physiology. Lung cellular and molecular physiology. L755-63.
    2008 Heat shock protein 90 inhibitors protect and restore pulmonary endothelial barrier function.American Journal of Respiratory Cell and Molecular Biology. 551-9.
    2008 Pulmonary capillary endothelial metabolic dysfunction: severity in pulmonary arterial hypertension related to connective tissue disease versus idiopathic pulmonary arterial hypertension.Arthritis and Rheumatism. 1156-64.
    2008 Pulmonary capillary endothelial metabolic function in chronic thromboembolic pulmonary hypertension.Journal of thrombosis and haemostasis : JTH. 1275-80.
    2007 Chaperone-dependent E3 ligase CHIP ubiquitinates and mediates proteasomal degradation of soluble guanylyl cyclase.American journal of physiology. Heart and circulatory physiology. H3080-7.
    2007 Estrogen as a new therapeutic target for asthma and chronic obstructive pulmonary disease.Drug news & perspectives. 241-52.
    2007 Functional significance of hsp90 complexes with NOS and sGC in endothelial cells.Clinical hemorheology and microcirculation. 19-35.
    2007 Heat shock protein 90 inhibitors prolong survival, attenuate inflammation, and reduce lung injury in murine sepsis.American journal of respiratory and critical care medicine. 667-75.
    2007 Nitric oxide preconditioning regulates endothelial monolayer integrity via the heat shock protein 90-soluble guanylate cyclase pathway.American journal of physiology. Heart and circulatory physiology. H893-903.
    2007 The green tea polyphenol epigallocatechin-3-gallate improves systemic hemodynamics and survival in rodent models of polymicrobial sepsis.Shock (Augusta, Ga.). 353-9.
    2007 Vascular endothelium summary statement I: Health promotion and chronic disease prevention.Vascular pharmacology. 315-7.
    2007 Vascular endothelium summary statement VI: Research directions for the 21st century.Vascular pharmacology. 330-2.
    2006 Angiotensin, bradykinin and the endothelium.Handbook of experimental pharmacology. 255-94.
    2006 Effects of hsp90 binding inhibitors on sGC-mediated vascular relaxation.American journal of physiology. Heart and circulatory physiology. H260-8.
    2006 Functional relevance of Golgi- and plasma membrane-localized endothelial NO synthase in reconstituted endothelial cells.Arteriosclerosis, thrombosis, and vascular biology. 1015-21.
    2006 Nitric oxide and the endothelium: history and impact on cardiovascular disease.Vascular pharmacology. 268-76.
    2005 Estrogen reduces carbachol-induced constriction of asthmatic airways by stimulating large-conductance voltage and calcium-dependent potassium channels.American Journal of Respiratory Cell and Molecular Biology. 239-47.
    2005 Extracellular hsp70 levels in children with septic shock.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 308-11.
    2005 Hyperglycemia and reactive oxygen species mediate apoptosis in aortic endothelial cells through Janus kinase 2.Vascular pharmacology. 320-6.
    2005 Interaction between the 90-kDa heat shock protein and soluble guanylyl cyclase: physiological significance and mapping of the domains mediating binding.Molecular pharmacology. 1133-41.
    2004 Angiotensin-converting enzyme activity: a novel way of assessing pulmonary changes during total knee arthroplasty.Anesthesia and analgesia. 1018-23, table of contents.
    2004 CDC/AHA Workshop on Markers of Inflammation and Cardiovascular Disease: Application to Clinical and Public Health Practice: report from the laboratory science discussion group.Circulation. e545-9.
    2004 Epigallocatechin-3-gallate, a green tea-derived polyphenol, inhibits IL-1 beta-dependent proinflammatory signal transduction in cultured respiratory epithelial cells.The Journal of nutrition. 1039-44.
    2004 Reduced pulmonary endothelium-bound angiotensin converting enzyme activity in diabetic rabbits.Vascular pharmacology. 159-65.
    2004 beta-hydroxybutyrate induces acute pulmonary endothelial dysfunction in rabbits.Experimental lung research. 193-206.
    2003 Estradiol relaxes rat aorta via endothelium-dependent and -independent mechanisms.Pharmacology. 20-6.
    2003 Novel complexes of guanylate cyclase with heat shock protein 90 and nitric oxide synthase.American journal of physiology. Heart and circulatory physiology. H669-78.
    2002 C/EBP-beta mediates iNOS induction by hypoxia in rat pulmonary microvascular smooth muscle cells.Circulation research. 125-7.
    2002 Endothelium-independent effect of estrogen on Ca(2+)-activated K(+) channels in human coronary artery smooth muscle cells.Cardiovascular Research. 650-61.
    2002 Molecular mechanisms of iNOS induction by IL-1 beta and IFN-gamma in rat aortic smooth muscle cells.American journal of physiology. Cell physiology. C144-52.
    2001 Angiotensin II relaxes microvessels via the AT(2) receptor and Ca(2+)-activated K(+) (BK(Ca)) channels.Hypertension. 301-7.
    2001 Long-term antioxidant administration attenuates mineralocorticoid hypertension and renal inflammatory response.Hypertension. 781-6.
    2001 Nitric oxide differentially regulates induction of type II nitric oxide synthase in rat vascular smooth muscle cells versus macrophages.Arteriosclerosis, thrombosis, and vascular biology. 529-35.
    2001 Pulmonary capillary endothelial dysfunction in early systemic sclerosis.Arthritis and Rheumatism. 902-11.
    2001 Regulation of the nitric oxide synthase-nitric oxide-cGMP pathway in rat mesenteric endothelial cells.Journal of applied physiology (Bethesda, Md. : 1985). 2553-60.
    2000 A reverse nuclear factor-kappaB element in the rat type II nitric oxide synthase promoter mediates the induction by interleukin-1beta and interferon-gamma in rat aortic smooth muscle cells.General pharmacology. 9-16.
    2000 Angiotensin converting enzyme in human synovium: increased stromal [(125)I]351A binding in rheumatoid arthritis.Annals of the rheumatic diseases. 125-31.
    2000 Effect of nitrite on endothelial function in isolated lung.General pharmacology. 401-8.
    2000 From the editor-in-chiefGeneral pharmacology. 1-2.
    2000 Non-NF-kappaB elements are required for full induction of the rat type II nitric oxide synthase in vascular smooth muscle cells.British journal of pharmacology. 270-8.
    2000 Pulmonary capillary endothelium-bound angiotensin-converting enzyme activity in acute lung injury.Circulation. 2011-8.
    2000 Quantification of eNOS mRNA in the canine cardiac vasculature by competitive PCR.American journal of physiology. Heart and circulatory physiology. H658-65.
    2000 Quantification of pulmonary capillary endothelium-bound angiotensin converting enzyme inhibition in man.General pharmacology. 213-8.
    2000 Reduced lung endothelial angiotensin-converting enzyme activity in Watanabe hyperlipidemic rabbits in vivo.American journal of physiology. Lung cellular and molecular physiology. L1280-8.
    1999 Pulmonary capillary endothelium-bound angiotensin-converting enzyme activity in humans.Circulation. 1593-9.
    1999 Vascular recruitment increases evidence of lung injury.Critical Care Medicine. 120-9.
    1998 Cross-tolerance between endogenous nitric oxide and exogenous nitric oxide donors.European journal of pharmacology. 313-21.
    1998 Differential action of angiotensin II and activity of angiotensin-converting enzyme in human bypass grafts.The Journal of thoracic and cardiovascular surgery. 206-12.
    1998 Differential distribution of angiotensin AT2 receptors in the normal and failing human heart.The Journal of pharmacology and experimental therapeutics. 323-36.
    1998 Effect of acute coronary occlusion on the size of the dynamically perfused coronary capillary bed in the dog.Microvascular research. 95-103.
    1998 Effects of antisense oligonucleotide to iNOS on hemodynamic and vascular changes induced by LPS.The American journal of physiology. H1078-83.
    1998 Expression of functional angiotensin-converting enzyme and AT1 receptors in cultured human cardiac fibroblasts.Circulation. 2553-9.
    1998 Induction of nitric oxide synthase by protein synthesis inhibition in aortic smooth muscle cells.British journal of pharmacology. 1000-8.
    1998 Molecular cloning and analysis of the rat inducible nitric oxide synthase gene promoter in aortic smooth muscle cells.Biochemical pharmacology. 1873-80.
    1998 Release of a leukocyte activation inhibitor by staurosporine-treated pulmonary artery endothelial cells.The American journal of physiology. L184-92.
    1998 Unaltered pulmonary capillary surface area in the presence of changing arterial resistance.The American journal of physiology. L264-9.
    1998 Zn2+ inhibits nitric oxide formation in response to lipopolysaccharides: implication in its anti-inflammatory activity.European journal of pharmacology. 265-72.
    1997 Endothelial ectoenzyme assays estimate perfused capillary surface area in the dog lung.Microvascular research. 145-55.
    1997 Sequential development of angiotensin receptors and angiotensin I converting enzyme during angiogenesis in the rat subcutaneous sponge granuloma.British journal of pharmacology. 1302-11.
    1996 Aminopeptidase P is disposed on human endothelial cells.Immunopharmacology. 149-52.
    1996 Anesthesia with sodium pentobarbital enhances lipopolysaccharide-induced cardiovascular dysfunction in rats.Shock (Augusta, Ga.). 365-70.
    1996 Cholera toxin enhances taurine uptake in cultures of human retinal pigment epithelial cells.Current eye research. 229-36.
    1996 Cytoskeleton-dependent activation of the inducible nitric oxide synthase in cultured aortic smooth muscle cells.British journal of pharmacology. 1085-94.
    1996 Downregulation of nitrovasodilator-induced cyclic GMP accumulation in cells exposed to endotoxin or interleukin-1 beta.British journal of pharmacology. 1359-66.
    1996 Human aortic endothelial cell aminopeptidase N.Immunopharmacology. 153-6.
    1996 Measurement of pulmonary blood flow by fractal analysis of flow heterogeneity in isolated canine lungs.Journal of applied physiology (Bethesda, Md. : 1985). 2039-45.
    1996 Mechanisms of tolerance to sodium nitroprusside in rat cultured aortic smooth muscle cells.British journal of pharmacology. 147-55.
    1996 Monocyte- and cytokine-induced downregulation of angiotensin-converting enzyme in cultured human and porcine endothelial cells.Circulation research. 512-23.
    1996 Monocyte-induced downregulation of nitric oxide synthase in cultured aortic endothelial cells.Arteriosclerosis, thrombosis, and vascular biology. 1095-103.
    1996 Relationship between volume of bathing medium and ectoenzyme activity in monolayers of cultured BPAEC.The American journal of physiology. L464-9.
    1996 cGMP accumulation and gene expression of soluble guanylate cyclase in human vascular tissue.Journal of cellular physiology. 213-21.
    1995 Cyclic AMP-independent up-regulation of the human serotonin transporter by staurosporine in choriocarcinoma cells.The Journal of biological chemistry. 17189-95.
    1995 HP-228, a novel synthetic peptide, inhibits the induction of nitric oxide synthase in vivo but not in vitro.The Journal of pharmacology and experimental therapeutics. 584-91.
    1995 Regulation of fluid-phase endocytosis in alveolar macrophages.The American journal of physiology. L520-6.
    1995 Regulation of taurine transport by Escherichia coli heat-stable enterotoxin and guanylin in human intestinal cell lines.The Journal of clinical investigation. 361-9.
    1995 Regulation of vascular smooth muscle soluble guanylate cyclase activity, mRNA, and protein levels by cAMP-elevating agents.Hypertension. 696-704.
    1994 Assay of pulmonary microvascular endothelial angiotensin-converting enzyme in vivo: comparison of three probes.Toxicology and applied pharmacology. 99-111.
    1994 Effect of high blood flow on pulmonary vascular permeability to protein.Journal of applied physiology (Bethesda, Md. : 1985). 2342-7.
    1994 Estimation of rate constants for reactions of pulmonary microvascular angiotensin converting enzyme with an inhibitor and a substrate in vivo.The Journal of pharmacology and experimental therapeutics. 260-8.
    1994 Radiation-induced early pulmonary endothelial ectoenzyme dysfunction in vivo: effect of indomethacin.Toxicology and applied pharmacology. 112-22.
    1994 Smooth muscle cell responsiveness to nitrovasodilators in hypertensive and normotensive rats.Hypertension. 476-84.
    1993 Neutrophil-mediated endothelial angiotensin-converting enzyme dysfunction: role of oxygen-derived free radicals.The American journal of physiology. L243-9.
    1993 Prevention of nitric oxide synthase induction in vascular smooth muscle cells by microtubule depolymerizing agents.British journal of pharmacology. 603-5.
    1993 Radiation-induced alterations in angiotensin converting enzyme activity in cultured bovine pulmonary arterial endothelial cell monolayers.Toxicology and applied pharmacology. 96-105.
    1993 Sulfhydryl-depleting agents, but not deferoxamine, modulate EDRF action in cultured pulmonary arterial cells.The American journal of physiology. L220-7.
    1993 Tyrosine kinase inhibitors suppress endotoxin- and IL-1 beta-induced NO synthesis in aortic smooth muscle cells.The American journal of physiology. H1014-8.
    1992 Effects of indomethacin on PMA-induced pulmonary endothelial enzyme dysfunction in vivo.The American journal of physiology. L153-62.
    1992 Effects of oxidant stress on endothelium-derived relaxing factor-induced and nitrovasodilator-induced cGMP accumulation in vascular cells in culture.Circulation research. 326-40.
    1992 Endothelial cGMP does not regulate basal release of endothelium-derived relaxing factor in culture.The American journal of physiology. L113-21.
    1992 Influence of vascular smooth muscle heterogeneity on angiotensin converting enzyme activity in chicken embryonic aorta and in endothelial cells in culture.Circulation research. 923-31.
    1992 Methylene blue inhibits nitrovasodilator- and endothelium-derived relaxing factor-induced cyclic GMP accumulation in cultured pulmonary arterial smooth muscle cells via generation of superoxide anion.The Journal of pharmacology and experimental therapeutics. 170-9.
    1992 Muscarinic binding sites on bovine pulmonary arterial endothelial cells in culture.Pharmacology. 324-33.
    1992 PMA-activated neutrophils decrease ectoenzyme activities in rabbit aortic endothelial cells in culture.The American journal of physiology. L657-63.
    1992 PMA-activated neutrophils decrease pulmonary endothelial ectoenzyme activities in perfused rabbit lungs.The American journal of physiology. L650-6.
    1991 Effects of blood flow on lung ACE kinetics: evidence for microvascular recruitment.Journal of applied physiology (Bethesda, Md. : 1985). 2244-54.
    1991 Multiple muscarinic receptor subtypes in the canine pulmonary circulation.Journal of applied physiology (Bethesda, Md. : 1985). 2032-43.
    1991 Species variation in pulmonary endothelial aminopeptidase P activity.The Journal of pharmacology and experimental therapeutics. 1301-7.
    1991 The nature of muscarinic receptor subtypes mediating pulmonary vasoconstriction in the rabbit.Pulmonary pharmacology. 8-19.
    1990 Effects of adenosine and analogs on adenylate cyclase activity in cultured bovine aortic endothelial cells.Biochemical pharmacology. 1103-9.
    1990 Effects of arachidonic acid in the rabbit pulmonary and systemic vascular beds in vivo.Pharmacology. 60-8.
    1990 Endothelium removal does not abolish angiotensin converting enzyme activity from the mesenteric arterial bed of the rat.Biochemical pharmacology. 1149-51.
    1990 Inhibition of endothelial-bound angiotensin converting enzyme, in vivo.British journal of pharmacology. 121-7.
    1989 Angiotensin converting enzyme activity is present in the endothelium-denuded aorta.British journal of pharmacology. 333-5.
    1989 Dichotomous actions of endothelium-derived factors in modulating vasomotor tone in rabbit pulmonary arteries.Pulmonary pharmacology. 55-8.
    1989 Modulation of adenylate cyclase activity in cultured bovine pulmonary arterial endothelial cells. Effects of adenosine and derivatives.Biochemical pharmacology. 423-30.
    1989 Muscarinic receptor subtype (M1) identification on rabbit pulmonary vascular endothelium in vivo.Pharmacology. 253-64.
    1988 Early effects of ionizing radiation on pulmonary endothelial angiotensin-converting enzyme and 5'-nucleotidase, in vivo.Toxicology and applied pharmacology. 342-55.
    1988 Monitoring of pulmonary endothelial enzyme function: an animal model for a simplified clinically applicable procedure.Anesthesiology. 44-52.
    1987 Early pulmonary endothelial enzyme dysfunction after phorbol ester in conscious rabbits.Journal of applied physiology (Bethesda, Md. : 1985). 1972-8.
    1987 Effects of acid-base imbalance on pulmonary angiotensin-converting enzyme in vivo.Journal of applied physiology (Bethesda, Md. : 1985). 1629-37.
    1986 Acetylcholine-induced contractions in isolated rabbit pulmonary arteries: role of thromboxane A2.The Journal of pharmacology and experimental therapeutics. 535-41.
    1986 Effects of alveolar pressure on lung angiotensin-converting enzyme function in vivo.Journal of applied physiology (Bethesda, Md. : 1985). 1041-50.
    1986 Effects of an i.v. lethal dose of 3,4-methylenedioxyamphetamine (MDA) in the dog and antagonism by chlorpromazine.General pharmacology. 179-83.
    1986 Effects of anesthesia and phenoxybenzamine on responses of dogs to IV subtoxic doses of 3,4-methylenedioxyamphetamine (MDA).Archives internationales de pharmacodynamie et de therapie. 240-51.
    1986 In vivo determinations of Ki values for angiotensin converting enzyme inhibitors.Advances in experimental medicine and biology. 453-9.
    1986 Michaelis-Menten kinetics of pulmonary endothelial angiotensin converting enzyme in the conscious rabbit.Advances in experimental medicine and biology. 445-51.
    1986 Prostanoid inhibition potentiates vasoconstrictor response to acetylcholine in dog lung.Journal of applied physiology (Bethesda, Md. : 1985). 1035-40.
    1986 Prostanoid mediation of pulmonary vascular response to acetylcholine in rabbits.The American journal of physiology. H808-14.
    1985 Plasmalemmal metabolic activities in cultured calf pulmonary arterial endothelial cells.Research communications in chemical pathology and pharmacology. 163-79.
    1984 Effects of acetylcholine in the pulmonary circulation of rabbits.The Journal of pharmacology and experimental therapeutics. 236-41.
    1984 Kinetics of pulmonary angiotensin-converting enzyme and 5'-nucleotidase in vivo.Journal of applied physiology: respiratory, environmental and exercise physiology. 1173-81.
    1984 Removal of adenosine from the rabbit pulmonary circulation, in vivo and in vitro.Circulation research. 603-11.
    1983 Prolonged reduction in serum angiotensin converting enzyme activity after treatment of rabbits with bleomycin.Toxicology and applied pharmacology. 276-82.
    1983 Pulmonary endothelial dysfunction in the presence or absence of interstitial injury induced by intratracheally injected bleomycin in rabbits.The American review of respiratory disease. 740-6.
    1983 Single-pass removal of [14C]-5-hydroxytryptamine and [3H]norepinephrine by rabbit lung, in vivo: kinetics and sites of removal.The Journal of pharmacology and experimental therapeutics. 28-33.
    1982 Altered removal of vasoactive substances in the injured lung: detection of lung microvascular injury.Annals of the New York Academy of Sciences. 458-74.
    1982 Early detection of oxygen-induced lung injury in conscious rabbits. Reduced in vivo activity of angiotensin converting enzyme and removal of 5-hydroxytryptamine.The American review of respiratory disease. 534-9.
    1981 Acute cocaine intoxication in the conscious dog: studies on the mechanism of lethality.The Journal of pharmacology and experimental therapeutics. 350-6.
    1981 Biochemical markers of bleomycin toxicity: clearance of [14C]-5-hydroxytryptamine and [3H]norepinephrine by rabbit lung in vivo.The Journal of pharmacology and experimental therapeutics. 524-9.
    1981 Metabolism of [3H]benzoyl-phenylalanyl-alanyl-proline by pulmonary angiotensin converting enzyme in vivo: effects of bradykinin, SQ 14225 or acute hypoxia.The Journal of pharmacology and experimental therapeutics. 263-70.
    1981 Reduction in rabbit serum and pulmonary angiotensin converting enzyme activity after subacute bleomycin treatment.Biochemical pharmacology. 2577-84.
    1980 Pulmonary clearance of [14C]-5-hydroxytryptamine and [3H]norepinephrine in vivo: effects of pretreatment with imipramine or cocaine.The Journal of pharmacology and experimental therapeutics. 120-7.
    1978 Acute cocaine intoxication in the conscious dog: pathophysiologic profile of acute lethality.Archives internationales de pharmacodynamie et de therapie. 328-40.
    1978 Effect of 1-alpha-acetylmethadol (LAAM) on various physiological parameters in the conscious dog.Archives internationales de pharmacodynamie et de therapie. 157-67.
    1977 The effects of haloperidol, chlorpromazine and propranolol on acute amphetamine poisoning in the conscious dog.The Journal of pharmacology and experimental therapeutics. 230-43.
    1975 Letter: Haloperidol for acute amphetamine poisoning: a study in dogs.JAMA. 1340-1.

    Full Name

  • John Catravas