Overview

  • Yale University School of Medicine- Postdoctoral Associate, HHMI postdoctoral Associate and Associate Research Scientist (ARS)Cologne University- PhD in Medical Biochemistry and Research Scientist
  • Selected Publications

    Articles In Academic Journals

    Year Title
    2018 Coordination of different ligands to copper(II) and cobalt(III) metal centers enhances Zika virus and dengue virus loads in both arthropod cells and human keratinocytes.Biochimica et biophysica acta. 40-50.
    2018 Exosomes serve as novel modes of tick-borne flavivirus transmission from arthropod to human cells and facilitates dissemination of viral RNA and proteins to the vertebrate neuronal cellsPLoS pathogens. e1006764.
    2017 An in vitro blood-feeding method revealed differential Borrelia turicatae (Spirochaetales: Spirochaetaceae) gene expression after spirochete acquisition and colonization in the soft tick Ornithodoroos turicata (Acari: Argasidae)
    2017 Arthropod exosomes as novel transmission blocking strategies for vector-borne pathogensAmerican Journal of Tropical Medicine and Hygiene. 32.
    2017 Coordination of different complexes to copper(II) and cobalt(III) metal centers enhances Zika virus and dengue virus loads in both arthropod cells and human keratinocytesBiochimica et biophysica acta.
    2017 Human rickettsial pathogen modulates arthropod organic anion transporting polypeptide and tryptophan pathway for its survival in ticksScientific Reports. 1-13.
    2017 Identification and characterization of a histamine-binding lipocalin-like molecule from the relapsing fever tick ornithodoros turicataInsect Molecular Biology. 1-11.
    2016 An in vitro blood-feeding method revealed differential Borrelia turicatae (Spirochaetales: Spirochaetaceae) gene expression after spirochete acquisition and colonization in the soft tick Ornithodoros turicata (Acari: Argasidae)J Med Entomol. 1-9.
    2016 Molecular Identification and bioinformatics analysis of a potential anti-vector vaccine candidate, 15 kDa salivary gland protein (Salp15), homologues from Ixodes affinis ticks
    2016 Molecular identification and bioinformatics analysis of a potential anti-vector vaccine candidate, 15-kDa salivary gland protein (Salp15), from Ixodes affinis ticksTicks and tick-borne diseases.
    2016 Viral receptors of the gut: vector-borne viruses of medical importanceCurrent opinion in insect science. 44-50.
    2015 Identification and comparative analysis of subolesin/akirin ortholog from Ornithodoros turicata ticksParasites & vectors. 132.
    2015 Transmission-Blocking Vaccines: Focus on Anti-Vector Vaccines against Tick-Borne DiseasesArchivum immunologiae et therapiae experimentalis. 169-79.
    2014 Antivirulence properties of an antifreeze proteinCell reports. 417-24.
    2012 Ectopic expression of cyclase associated protein CAP restores the streaming and aggregation defects of adenylyl cyclase a deficient Dictyostelium discoideum cellsBMC developmental biology. 3.
    2012 Expression of Ixodes scapularis antifreeze glycoprotein enhances cold tolerance in Drosophila melanogasterPLOS ONE. e33447.
    2012 Semaphorin 7A contributes to West Nile virus pathogenesis through TGF-?1/Smad6 signalingJournal of immunology (Baltimore, Md. : 1950). 3150-8.
    2012 Semaphorin 7A contributes to West Nile virus pathogenesis through TGF-beta1/Smad6 signalingJ Immunol. 3150-8.
    2010 Anaplasma phagocytophilum induces Ixodes scapularis ticks to express an antifreeze glycoprotein gene that enhances their survival in the coldThe Journal of clinical investigation. 3179-90.
    2010 Anaplasma phagocytophilum induces actin phosphorylation to selectively regulate gene transcription in Ixodes scapularis ticksThe Journal of experimental medicine. 1727-43.
    2010 Caspase-12 controls West Nile virus infection via the viral RNA receptor RIG-INat Immunol. 912-9.
    2009 Fusion loop peptide of the West Nile virus envelope protein is essential for pathogenesis and is recognized by a therapeutic cross-reactive human monoclonal antibodyJournal of immunology (Baltimore, Md. : 1950). 650-60.
    2009 Microarray phenotyping places cyclase associated protein CAP at the crossroad of signaling pathways reorganizing the actin cytoskeleton in DictyosteliumExperimental cell research. 127-40.
    2008 RNA interference screen for human genes associated with West Nile virus infectionNature. 242-5.
    2007 Regulation of Neuronal Morphogenesis by Abl Family KinasesSpringer. 180-194.
    2005 Cyclase-associated protein is essential for the functioning of the endo-lysosomal system and provides a link to the actin cytoskeletonTraffic. 930-46.
    2004 Cyclase associated protein CAP in the regulation of the actin cytoskeleton and cell polarity in Dictyostelium discoideumPhD thesis, University of Cologne, Germany.
    2004 The cyclase-associated protein CAP as regulator of cell polarity and cAMP signaling in DictyosteliumMol Biol Cell. 934-45.

    Chapters

    Year Title
    2014 Bacterial, Protozoan and Viral Life-threatening DiseasesDiseases and Theranostics, Biotechnology (multi-volume set). Studium Press LLC.
    2014 Vector-borne diseasesDiseases and Theranostics, Biotechnology (multi-volume set). Studium Press LLC.

    Research Overview

  • Infectious Diseases, Arthropod-borne Diseases, Flaviviruses interactions with vector and vertebrate host (flaviviruses such as West Nile virus, Dengue and tick-borne encephalitis Powassan and Langat viruses are studied in our Laboratories), Microbial Pathogenesis, Host Immune Responses, Host-pathogen Interactions, microbe induced cellular mechanisms, Molecular & Cellular biology
  • Expertise Keywords

  • Biology : Cell Signaling, Actin Cytoskeleton
  • Biotechnology : Molecular Biology and Genetics
  • Health : Medicine, Infectious Diseaes and Clinical Microbiology
  • Microbiology : Infectious Diseases, Virology, Vaccine development, Transmission Blocking Vaccines, Immunology, Host-Pathogen Interactions, Cellular Microbiology
  • Education And Training

  • Ph.D. in Medical Biochemistry, University of Cologne 2004
  • Full Name

  • Hameeda Sultana