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Erin Purcell
ASSISTANT PROFESSOR
epurcell@odu.edu
757-683-4240
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Erin Purcell
ASSISTANT PROFESSOR
Publications
Research
Background
Contact
Publications
Selected Publications
Articles In Academic Journals
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Year
Title
2017
A nutrient-regulated cyclic diguanylate phosphodiesterase controls Clostridium difficile biofilm and toxin production during stationary phase
.
Infection and immunity
. 1-17.
2016
Cyclic diguanylate signaling in Gram-positive bacteria
.
FEMS microbiology reviews
. 753-73.
2015
Cyclic di-GMP riboswitch-regulated type IV pili contribute to aggregation of Clostridium difficile
.
Journal of bacteriology
. 819-32.
2015
Regulation of Type IV Pili Contributes to Surface Behaviors of Historical and Epidemic Strains of Clostridium difficile
.
Journal of bacteriology
. 565-77.
2013
Identification and characterization of cyclic nucleotide phosphodiesterases
.
Methods in molecular biology (Clifton, N.J.)
. 235-43.
2013
The second messenger cyclic Di-GMP regulates Clostridium difficile toxin production by controlling expression of sigD
.
Journal of bacteriology
. 5174-85.
2012
Cyclic diguanylate inversely regulates motility and aggregation in Clostridium difficile
.
Journal of bacteriology
. 3307-16.
2010
An analysis of the solution structure and signaling mechanism of LovK, a sensor histidine kinase integrating light and redox signals
.
Biochemistry
. 6761-70.
2010
Electronic and protein structural dynamics of a photosensory histidine kinase
.
Biochemistry
. 4752-9.
2008
Photoregulation in prokaryotes
.
Current opinion in microbiology
. 168-78.
2008
Two-component signaling systems and cell cycle control in Caulobacter crescentus
.
Advances in experimental medicine and biology
. 122-30.
2007
A photosensory two-component system regulates bacterial cell attachment
.
Proceedings of the National Academy of Sciences of the United States of America
. 18241-6.
2007
Structure of the redox sensor domain of Azotobacter vinelandii NifL at atomic resolution: signaling, dimerization, and mechanism
.
Biochemistry
. 3614-23.
2004
Purification and initial characterization of a putative blue light-regulated phosphodiesterase from Escherichia coli
.
Photochemistry and photobiology
. 542-7.
Research
Research Overview
small molecule signaling contributing to virulence and persistence in Clostridium difficile
Grants
Investigating Cutibacterium acnes inactivation by Nanosecond Pulse Stimulation
awarded by
Pulse Biosciences
2019
Clostridium difficile motility in response to reactive oxygen species
awarded by
Old Dominion University office of Research
2018
The Role of the Stringent Response in Clostridium difficile Survival and Virulence
awarded by
NIH/NIAID
2016 - 2018
Expertise Keywords
Microbiology :
Signal transduction, bacterial antibiotic resistance
Background
Education And Training
Ph.D. in Biochemistry and Molecular Biology,
The University of Chicago
2011
Contact
Full Name
Erin
Purcell