Selected Publications

Articles In Academic Journals

Year Title
2014 Aneurismal lesions of patients with abdominal aortic aneurism contain clonally expanded T cellsJournal of Immunology. 4897-912.
2009 Differential expression of CD3-Zeta message and protein in tumor infiltrating lymphocytes from solid tumor specimens and malignant ascites from patients with ovarian carcinomaAnticancer Research. 4673-4682.
2007 Human Autoimmune Diseases are Specific Antigen-Driven T-Cell Diseases: Identification of the AntigensImmunologic Research. 359-372.
2006 The Abdominal Aortic Aneurysm (AAA) is a specific antigen-driven T-cell diseaseAnnals of the New York Academy of Science. 224-235.
2005 Oligoclonal T cells are infiltrating the brain of children with AIDS: Sequence analysis revealed high proportions of identical beta-chain T-cell receptor (TCR) transcriptsClinical and Experimental Immunology. 338-356.
2004 Theiler's Virus Infection: A Model for Multiple SclerosisClinical Microbiology Reviews. 174-207.
2003 Apoptosis of infiltrating T cells in the CNS of mice infected with Theiler's Murine encephalomyelitis virus (TMEV)Virology. 110-123.
2003 Identical alpha-chain T-cell receptor transcripts are present on T cells infiltrating coronary arteries of cardiac allografts with chronic rejectionCellular Immunology. 75-90.
2001 Apoptosis in chronic rejection of human cardiac allograftsTransplantation. 1137-1146.
2001 Immunopathology of secondary-progressive multiple sclerosisAnnales of Neurology. 646-657.
2001 Oligoclonal T cells are present in the CSF of a child with a recurrent disseminated MS-like demyelinating disease following Hepatitis A infectionClinical and Diagnostic Laboratory Immunology. 984-92.
2001 Oligoclonal T cells are present in the CSF of a child with a recurrent disseminated MS-like demyelinating disease follwing Hepatitis A infectonClinical and Diagnostic Laboratory Immunology. 984-992.
2000 Differential expression of TGF-beta, IL-2 and other cytokines in the CNS of TMEV-infected susceptible and resistant strains of miceVirology. 346-360.
1999 Angiocentric CD3+ T-cell infiltrates in HIV-1 associate CNS disease in childrenClinical and Diagnostic Laboratory Immunology. 105-114.
1999 Angiocentric CD3+ T-cell infiltrates in Human immunodeficiency virus type-1-associated central nervous system disease in childrenClinical and Diagnostic Laboratory Immunology. 105-114.
1998 Amplification of T-cell receptor alpha- and beta-chain transcripts from mouse spleen lymphocytes by the nonpalindromic adaptor polymerase chain reactionHematopathology and Molecular Hematology. 73-88.
1998 Amplification of T-cell receptor alpha- and beta-chain transcripts from mouse spleen lymphocytes by the nonpalindromic adaptor polymerase chain reaction. Hematopathology and Molecular Hematology 11 73-88 1998Hematopathology and Molecular Hematology. 73-88.
1998 Amplification of murine alpha and beta-chain T-cell receptor transcripts by the nonpalindromic adaptor polymerase chain reactionHematopathology and Molecular Hemtology. 73-88.
1998 iNOS and nitrotryosine are found in monocyte/macrophages and/or astrocytes in acute but not in chronic multiple sclerosis lesionsClinical and Diagnostic Laboratory Immunology. 438-445.
1997 An anti-LFA-1 monoclonal antibody (LDA-8) induces cellular aggregation of human lymphoblastoid cell lines and peripheral blood lymphocytesHematopathology and Molecular Hematology. 29-40.
1997 An anti-LFA-1 monoclonal antibody induces cellular aggregation of human lymphoblastoid cell lines and peripheral blood lymphocytesHematopathology and Molecular Hemtology. 29-40.
1997 Inducible nitric oxide synthase in Theiler's Murine Encephalomyelitis Virus infectionJournal of Virology. 3228-3235.
1995 Immunology of Theiler's Murine Encephalomyelitis Virus infectionImmunologic Research. 13-33.
1995 Molecular mimicry between Fc receptor and S peplomer protein of MHV, BCV and TGEVHybridoma. 1-8.
1994 Molecular mimicry between Fc receptors and viral antigensArchivum Immunologiae at Therapie Experimentalis. 83-88.
1993 Molecular mimicry between S peplomer proteins of coronaviridae (MHV, BCV, TGEV and IBV) and Fc receptorAdvances in Experimental Biology and Medicine. 183-188.
1992 Human T-cell hybridoma-derived suppressor factor 160 and transforming growth factor-beta are different moleculesLympokine and Cytokine Research. 307-315.
1992 MHV S Peplomer protein expressed by a recombinant vaccinia virus vector exhibits IgG Fc-like binding activityVirology. 122-132.
1992 Microheterogeneity of S glycoprotein of mouse hepatitis virus temperature sensitive mutantsJournal of Virological Methods. 103-112.
1991 Fc receptor-like activity of mouse hepatitis virus E2 glycoproteinAdvances in Experimental Biology and Medicine. 51-58.
1991 Hybridoma-derived human suppressor factors: Inhibition of growth of tumor cell lines and effect on cytotoxic cellsHuman Antibodies and Hybridomas. 160-169.
1990 Immunoglobulin Fc binding activity is associatd with the mouse hepatitis virus E2 peplomer proteinVirology. 70-80.
1990 Mouse hepatitis virus gene B ORF1 is expressed in the cytoplasm of mouse fibroblasts and glial cellsVirology. 605-607.
1990 Persistent infection of an oligodendroglioma cell line generates a Theiler's virus variant which fails to induce demyelinating disease in SJL/J miceJournal of General Virology. 2123-2132.
1989 Regulation of natural killer cytotoxicity by recombinant aplpha interferons. Augmentation by interferon alpha-7, an interferon similar to interferon alpha JAnticancer Research. 849-858.
1988 Differential effects of human alpha and gamma interferon on mixed lymphocyte culture and on T-cell-mediated cytotoxicity. Inhibition of proliferation but not of IL-2 production by alpha interferonsInternational Archives of Allergy and Applied Immunology. 361-369.
1988 Growth factor production by Creutzfeldt-Jacob disease cell linesJournal of Virology. 3103-3108.
1988 Inhibition of mitogenic activity of PDGF, EGF, and FGF by inteferon gammaExperimental cell research. 575-580.
1988 Isolation and characterization of two plaque size variants of Theiler's murine encephalomyelitis virus (DA strain)Journal of General Virology. 2413-2418.
1987 Theiler's murine encephalomyelitis: a model of demyelination and persistence of virusCRC Critical Reviews in Immunology. 325-365.
1986 Immunomodulation of human leukocytes by staphylococcal enterotoxin A, a gamma interferon inducer. Augmentation of natural killer cells and induction of suppressor cellsCellular Immunology. 371-385.
1986 In vitro transformation elicited by Creutzfeldt-Jacob-infected brain materialJournal of Neuropathology and Experimental Neurology. 489-502.
1985 Potentiation of the antiviral and anticellular activities of interferons by mixtures of HuIFN-gamma and HuIFN-alpha or HuIFN-betaJournal of Interferon Research. 361-372.
1983 Mouse monoclonal antibody with specificity for human interferon gammaHybridoma. 439-449.
1982 Biological evaluation of Wratizolin penetration from ointment to the skinArchivum Immunologiae at Therapie Experimentalis. 631-640.
1980 Antagonism in action between mouse or human interferon and platelet growth factorArchives of Virology. 291-296.
1980 Dextran T fractions substituted with Cibacron blue F3G A as carriers for mouse interferonArchivum Immunologiae at Therapie Experimentalis. 313-322.
1980 Double infection of BALB/c mice with Rauscher murine leukemia and Herpes simplex virus type 2Archivum Immunologiae at Therapie Experimentalis. 337-344.
1980 Platelet derived growth factor inhibits antiviral and anticellular action of interferon in synchronized mouse or human cellsJournal of Interferon Research. 37-49.
1979 Effect of antimouse type I interferon globulin on the evolution of Moloney sarcoma virus-induced disease in miceInternational Journal of Cancer. 445-449.
1979 Effects of anti-interferon serum on growth and regression of Moloney sarcoma virus-induced tumors in miceActa Biologica et Medica Germanica. 829-835.
1978 Application of antisera to interferon in studying oncogenic virusesArchivum Immunologiae at Therapie Experimentalis. 529-536.
1978 Effect of non-steroidal anti-inflammatory drugs on Maloney sarcoma virus inoculated miceExperientia. 1615-1616.

Books

Year Title
2005 Nitric oxide in TMEV. In Experimental Models of Multiple Sclerosis
1990 Analysis of T-cell receptor and immunoglobulin cDNAs by the nonpalindromic adaptor polymerase chain reaction.  Ed. 5.  Orlando, FL: Methods in Molecular Genetics, Academic Press, Inc..

Chapters

Year Title
1998 "Structure and function of the trimolecular complex: T-cell receptor/peptide/MHC"Current Topics in Biochemistry. Thessaloniki: Aristotelian University of Thessaloniki, Laboratory of Biochemistry Press.
1997 Structure and function of the trimolecular complex: T-cell receptor/peptide/MHC.Current Topics in Biochemistry. Thessaloniki: Aristotelian University of Thessaloniki, Laboratory of Biochemistry Press.
1990 Murine Coronavirus RNA SynthesisNew Aspects of positive-strand RNA viruses. Washington, DC: American Society for Microbiology Press.

Research Overview

  • Mechanisms of virally-induced demyelinating and neurodegenerative diseases. Autoimmunity.
  • Grants

  • T Cells in the Pathogenisis of Systemic Sclerosis  awarded by National Institutes of Health 2001 - 2009
  • T-cell receptors in Acute Multiple Sclerosis, grant RG2942  awarded by National Multiple Sclerosis Society 1998 - 2003
  • Estrogen and autoimmune disease  awarded by Wyeth-Ayerst Research 2000 - 2002
  • Program Project: Immunopathogenesis of chronic cardiac graft rejection, grant PO1 AI40160  awarded by National Institutes of Health 1996 - 2002
  • Hematopoietic Stem Cell Chimerism to Treat Diabetes  awarded by National Institutes of Health 1998 - 2001
  • Identification of Virus(es) Responsible for Schizophrenia by Analysis of T-cell Receptor Clonal Expansions in the Cerebrospinal Fluid  awarded by Stanley Foundation 1998 - 2000
  • Tumor Antigens Recognized by T Cells in Malignant Glioma  awarded by The Brain Tumor Society 1996 - 1998
  • Prevention and treatment of virally-induced MS-like autoimmune demyelinating disease by bone marrow transplantation  awarded by Elanor Naylor Dana Charitable Trust (Peer Review) 1994 - 1997
  • Mouse Hepatitis Virus-induced autoimmune disease: T-cell specificity and T-cell antigen receptors  awarded by Texas Higher Education Coordinating Board 1992 - 1994
  • The Role of Nonstructural Proteins During Infection with MHV-JHM, a Neurotropic Corona Virus  awarded by National Multiple Sclerosis Society 1990 - 1992
  • Research start-up funds for the laboratories of Drs. Platsoucas and Olezak  awarded by Old Dominion University 2007 -
  • Expertise Keywords

  • Biology : Neurovirology, Immunology
  • Education And Training

    Full Name

  • Emilia Oleszak