Selected Publications

Articles In Academic Journals

Year Title
2016 Highly fluorescent resorcinarene cavitand nanocapsules with efficient renal clearanceNanotechnology.
2016 Selective mutation accumulation: A computational model of paternal age effectBioinformatics. 3790-3797.
2015 Evolutionary Soft Co-Clustering Formulations, Algorithms and ApplicationsData Mining and Knowledge Discovery, Springer. 765-791.
2014 Design and study of efflux function of EFGP fused MexAB-OprM membrane transporter in Pseudomonas aeruginosaAnalyst. 3088-3096.
2014 Design and study of the efflux function of the EGFP fused MexAB-OprM membrane transporter in Pseudomonas aeruginosa using fluorescence spectroscopyAnalyst. 3088-3096.
2013 A mesh generation and machine learning framework forBMC Bioinformatics. 372.
2013 Silver Nanoparticles Induce Developmental Stage-Specific Embryonic Phenotypes in ZebrafishNANOSCALE. 11625-36.
2012 Enhanced killing effect of nanosecond pulse electric fields on PANC1 and Jurkat cell lines in the presence of Tween 80.The Journal of membrane biology. 611-6.
2011 Nanosecond pulse electrical fields used in conjunction with multi-wall carbon nanotubes as a potential tumor treatmentBiomed Mater. 011002.
2011 Nanosecond pulse electrical fields used in conjunction with multi-wall carbon nanotudes as a potential tumor treatmentBiomed Mater. 011002.
2011 Nanosecond pulse electrical fields used in conjunction with mutli-wall carbon nanotubes as a potential tumor treatment.Biomed Mater. 011002.
2010 Using Ionized Gases and Electromagnetic Fields Special Issue—Nonthermal Medical/Biological Applications Membrane Permeability and Cell Survival After Nanosecond Pulsed-Electric-Field Exposure—Significance of Exposure-Media CompositionIEEE Transactions on plasma science. 2948.
2009 A new pulsed electric field therapy for melanoma disrupts the tumor’s blood supply and causes complete remission without recurrenceInt J Cancer. 438-45.
2009 A new pulsed electric field therapy for melanoma disrupts tumor's blood supply and causes complete remission without recurrenceInt. J. Cancer. 438-445.
2008 Physical and in silico approaches identify DNA-PK in a Tax DNA-damage response interactomeRetrovirology.
2007 ACS Nano 2007, 1, 133–143CrossRef| PubMed| CAS| Web of Science® Times Cited.
2007 Bioelectric Effects of Nanosecond PulsesIEEE Trans. Diel. Electr. Insul.. 1088-1109.
2007 Bioelectric effects of intense nanosecond pulsesIEEE Transact Dielectrics Electrical Insul. 1088-1109.
2007 In vivo imaging of transport and biocompatibility of single silver nanoparticles in early development of zebrafish embryosACS Nano. 133-143.
2007 Molecular characterization, tissue-specific expression and RNAi knockdown of the first vitellogenin receptor from a tickInsect Biochem Molec Biol. 10.1016/j.ibmb.2007.01.005.
2007 Sequence and the developmental and tissue-specific regulation of the first complete vitellogenin messenger RNA from ticks responsible for heme sequestrationInsect Biochemistry and Molecular Biology. 363-74.
2007 Sequence and the developmental and tissue-specific regulation of the first vitellogenin messenger RNA from ticks responsible for heme sequestrationInsect Biochem Molec Biol. 10.1016/j.ibmb.2007.01.004.
2005 3,4-Methylendioxymethamphetamine activates nuclear factor-kappaB, increases intracellular calcium, and modulates gene transcription in rat heart cellsCardiovasc Toxicol. 301-310.
2005 3,4-Methylenedioxymethamphetamine activates nuclear factor-kappaB, increases intracellular calcium, and modulates gene transcription in rat heart cells.Cardiovascular Toxicology. 301-10.
2005 Cocaine increases intracellular calcium and reactive oxygen species, depolarizes, mitochondria and activates genes associated with heart failure and remodelingCardiovasc Toxicol. 377-390.
2005 In vivo role of 20-hydroxyecdysone in the regulation of the vitellogenin mRNA and egg development in the American dog tick, Dermacentor variabilis (Say).Journal of Insect Physiology. 1105-16.
2003 Genetic and transcriptional analysis of spindle checkpoint genes in bone marrow failure patientsBlood Cells Mol Dis. 307-311.
2002 Fluorescence in situ hybridization on sperm using alkaline denaturationBiotechniques. 266-7.
1999 Aneuploidy frequencies in semen fractions from ten oligoasthenoteratozoospermic patients donating sperm for intracytoplasmic sperm injection.Fertility and sterility. 472-8.
1998 Induction by nitriles of sex chromosome aneuploidy: tests of mechanism.Mutation research. 149-57.
1997 The Drosophila melanogaster RAD54 homolog, DmRAD54, is involved in the repair of radiation damage and recombination.Molecular and cellular biology. 6097-104.
1994 Cloning of human and mouse genes homologous to RAD52, a yeast gene involved in DNA repair and recombination.Mutation research. 295-305.
1994 Refractory ceramic fibers (RCFs) induce germline aneuploidy in Drosophila oocytes.Mutation research. 23-7.
1991 Aneuploidy in Drosophila, II. Further validation of the FIX and ZESTE genetic test systems employing female Drosophila melanogasterMutation research. 147-163.
1991 Chrysotile and amosite asbestos induce germ-line aneuploidy in DrosophilaMutation research. 9-13.
1991 Dichloroacetonitrile, a by-product of water chlorination, induces aneuploidy in DrosophilaMutation research. 85-91.
1990 Aneuploidy in Drosophila, I. Genetic test systems in the female Drosophila melanogaster for the rapid detection of chemically induced chromosome gain and chromosome lossMutation Research/Environmental Mutagenesis and Related Subjects. 319-326.
1990 Aneuploidy in drosophila. III: Aneuploidogens inhibit in vitro assembly of taxol-purified drosophila microtubulesEnvironmental and molecular mutagenesis. 217-224.
1989 5-Azacytidine induces sex chromosome loss and interchange in immature germ cells of Drosophila mei-9 males.Environmental and molecular mutagenesis. 135-45.
1989 The use of molecularly tagged P elements to monitor spontaneous and induced frequencies of transposon excision and transpositionProgress in nucleic acid research and molecular biology. 59-67.
1986 Current status of aneuploidy testing in DrosophilaMutation research. 71-87.
1986 Molecular analysis of chemically-induced mutations at the RpII215 locus of Drosophila melanogaster.Mutation research. 47-54.
1986 Tests for chemical-induced germline transposition in Drosophila melanogaster.Progress in clinical and biological research. 399-409.
1982 Apurinic endonuclease from Drosophila melanogaster: reduced enzymatic activity in excision-deficient mutants of the mei-9 and mus(2)201 Loci.Molecular & general genetics. 235-9.
1981 Third-chromosome mutagen-sensitive mutants of Drosophila melanogaterGenetics. 607-23.
1980 Evidence for an increase in X-ray-ray-induced translocation frequency in oocytes of caffeine-treated Drosophila femalesMutation research. 207-10.
1979 Effects of caffeine on maternal repair systems in Drosophila melanogasgter. Concentration-dependent reversals of the effects of caffeine on chromosome loss and autosome-autosome translocations induced by x-rays in the paternal genomeMutation research. 79-86.
1977 Survival of caffeine-fed adult males and females from strains of Drosophila melanogasterMutation research. 453-6.
1975 Preliminary evidence of the influence of caffeine concentration on modification of maternal repair of chromosome breaks induced by X-rays in the paternal genome of DrosophilaMutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 289-291.
1972 Measurement of radiation-induced dominant lethals in stage-14 oocytes of DrosophilaMutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 355-357.

Books

Year Title
1988 NIEHS 55106: Aneuploidy Testing in Drosophila
1987 Aneuploidy Testing in Drosophila
1986 Chemically-induced Transposition in Drosophila

Chapters

Year Title
1980 Biochemical characterization of repair-deficient mutants of DrosophilaDNA Repair and Mutagenesis in Eukaryotes. Basic Life Sciences.

Conference Papers

Year Title
2010 Discovering overlapping modules and bridge proteins in proteomic networks.  366-369.
2008 Nanosecond pulse generator with variable pulse duration for the study of pulse induced biological effects.  61-64.
2006 A prototype of the HumanVirus Interactome Resource (HVIR).  172-180.
2006 Biological effects of intense subnanosecond electrical pulses.  573-576.
2006 NIRT (II): Design of biocompatible nanoparticles for probing living cellular functions and their potential environmental impacts
2005 NIRT (I): Design of biocompatible nanoparticles for probing living cellular functions and their potential environmental impacts
2005 The architecture of a proteomic network in the Yeast.  265-276.
2002 Paternal origin of Y-chromosome-bearing cells in microchimeric nulligravid females with autoimmune disease..  491-491.
2001 Glutathione S-transferase theta and mu (GSTM1 and GSTT1) gene expression in patients with aplastic anemia and myelodysplastic syndrome..  250-250.
2001 Microchimerism for Y-chromosome bearing cells in nulligravid females presenting with pediatric autoimmune disease..  663-663.
1999 Aneuploidy in sperm from fifty-four oligoasthenoteratozoospermic patients undergoing intracytoplasmic sperm injection..  A353-A353.
1999 Genomic instability in bone marrow failure syndromes: High frequency of aneuploidy by fluorescence in situ hybridization and identification of a spindle checkpoint gene mutation..  674A-674A.
1999 Glutathione-S transferase (GSTT1 and GSTM1) null genotypes in patients with aplastic anemia and myelodysplastic syndromes..  675A-675A.
1999 Increased frequency of glutathione-S transferase (GSTT1) null genotype in patients with aplastic anemia and myelodysplastic syndromes..  A324-A324.
1979 DROSOPHILA DNA-REPAIR ENDONUCLEASE SPECIFIC FOR APURINIC-APYRIMIDINIC SITES IN DNA.  S91-S92.

Grants

  • New tools for real-time single molecule probing of chromatin dynamics and functions in single live cells  awarded by NSF 2018 - 2023
  • 3SEM: STEM Success in Science, Engineering and Mathematics  awarded by NSF 2017 - 2022
  • BR2M: Basic Research in Regenerative Medicine  awarded by Dept of Defense - ONR 2018 - 2021
  • IDW Badges  awarded by ODU QEP 2017 - 2018
  • Stem cell derived cartilage as precursors to bone healing on nanostructured scaffolds  awarded by Dept of Defense 2017 - 2018
  • Photostable Multiplexing Nanoassays For Real-Time Study of Embryonic STEM Cells  awarded by US Public Health Service (NIH) 2016 - 2018
  • An integrative approach to teaching undergraduate genetics and biochemistry  awarded by ODU CLT 2017
  • Nanoscaffolds support to aid osteogenesis and bone healing  awarded by ODU-URP 2017
  • Photostable multiplexing nanoassays for real-time study of embryonic stem cells  awarded by NIH 2015 - 2017
  • Teacher Immersion Residency Program 2009 - 2014
  • Robust, multifunctional, bio-compatible nanocapsules for intraoperative imaging and other biomedical applications  awarded by Multidisciplinary seed grant of the Office of Research of Old Dominion University 2011
  • Electrochemotherapy and nanomedicine combine to enhance tumor cell death  awarded by CHRB 2009 - 2010
  • Nanoassay for study of multidrug resistance in bacteria  awarded by National Institutes of Health 2006 - 2010
  • Design of nanoparticles for probing living cellular functions and their potential environmental impacts  awarded by National Science Foundation 2005 - 2009
  • Elucidation of protein structure networks and beyond  awarded by ODU-RF 2008
  • A prototype of the Human Virus Interactome Resource (HVIR)  awarded by ODU 2006
  • Gene expression technologies to establish biomarkers for Pfiesteria exposure in mammalian cells  awarded by Old Dominion University 2005
  • Development of a mouse model to investigate gender differences in drug-induced cardiovascular disease  awarded by Jeffress Memorial Trust 2004 - 2005
  • Principal Investigator:Cellular Toxicity of Metal Oxide Nanoparticles in Mammalian Cells  awarded by Old Dominion University Faculty Summer Fellowship - 2005
  • Assessment of Osteoinductivity and Processing of Allograft Bone and Soft Tissues  awarded by Life Net Transplant Services 1995 - 1996
  • Center for environmental biotechnology  awarded by Center for Innovative Technology 2004 -
  • Laboratory instruction in cellular and molecular biology  awarded by National Science Foundation 2004 -
  • Center for environmental biotechnology  awarded by Center for Innovative Technology 1989 -
  • Laboratory instruction in cellular and molecular biology  awarded by National Science Foundation 1989 -
  • Education And Training

  • Ph.D. in Biology, Brown University 1977
  • B.A. in Human Biology, Brown University 1971
  • Full Name

  • Christopher Osgood