Selected Publications

Articles In Academic Journals

Year Title
2016 Nanosecond Pulsed Platelet-Rich Plasma (nsPRP) Improves Mechanical and Electrical Cardiac Function Following Myocardial Reperfusion InjuryPhysiological Reports.
2015 Human platelet gel supernatant inactivates opportunistic wound pathogens on skinPlatelets. 13-16.
2014 Gene Electro transfer of plasmid encoding VEGF For Enhanced Expression and Perfusion in the Ischemic Swine HeartPLOS ONE. e115235.
2014 Gene Electro transfer of plasmid encoding VEGF Improves pVEGF expression and Perfusion In the Ischemic Swine HeartPLsoOne.
2014 Prevention of distal flap necrosis in a rat random flap model by gene electrotransfer delivering VEGF165 plasmid.J Gene Medicine. 55-65.
2013 Electroporation-mediated gene transfer directly to the swine heartGene Therapy. 151-7.
2012 Electroporation-mediated gene transfer directly to the swine heart.Gene Therapy.
2008 Nanosecond Pulse Electric Field (nanopulse): a Novel Non-ligand Agonist for Platelet ActivationArchives of Biochemistry and Biophysics. 240-248.
2007 Bioelectric Effects of Nanosecond PulsesIEEE Trans. Diel. Electr. Insul.. 1088-1109.
2007 Bioelectric effects of intense nanosecond pulsesIEEE Transact Dielectrics Electrical Insul. 1088-1109.
2005 3,4-Methylendioxymethamphetamine activates nuclear factor-kappaB, increases intracellular calcium, and modulates gene transcription in rat heart cellsCardiovasc Toxicol. 301-310.
2005 3,4-Methylenedioxymethamphetamine activates nuclear factor-kappaB, increases intracellular calcium, and modulates gene transcription in rat heart cellsCardiovascular Toxicology. 301-10.
2005 Cocaine increases intracellular calcium and reactive oxygen species, depolarizes, mitochondria and activates genes associated with heart failure and remodelingCardiovasc Toxicol. 377-390.
2003 Cocaine but not morphine causes the generation of reactive oxygen species and activation of NF?B in transiently co-transfected heart and renal epithelial cellsCardiovascular Toxicology. 141-151.
2003 Cocaine, not morphine, causes the generation of reactive oxygen species and activation of NF-kappaB in transiently cotransfected heart cells.Cardiovascular Toxicology. 141-51.
2002 Cocaine activates the renin angiotensin system in pregnant rabbits and alters the response to ischemiaCardiovascular Toxicology. 91.
1995 Effects of phenylephrine induced increase in arterial pressure and closure of the ductus arteriosus on the secretion of atrial natriuretic peptide and renin in the ovine fetusLife Sci. 31.
1995 Intrauterine exposure to cocaine increased plasma ANP but did not alter hypoxanthine concentrations in the sheep fetusLife Sci. 1689.
1990 Pharmacological evidence for involvement of the sympathetic nervous system in the increase in renin secretion produced by a low sodium diet in ratsLife Sci. 2317.
1990 Pulmonary vascular effects of exogenous atrial natriuretic peptide in sheep fetusesPed Res. 140.
1989 Renal and cardiovascular effects of atrial natriuretic peptide in the sheep fetusPediatric Res. 1.
1986 By 95 days of gestation CRF increases plasma ACTH and cortisol in ovine fetusesAm J Physiol. E422.
1985 By 94 days of gestation plasma cortisol increases block ACTH response of hypotension in lamb fetusesAm J Physiol. E350.
1985 Catecholamine responses in fetal lambs subjected to hemorrhageAm J Obstet Gynecol. 475.
1985 Corticotrophin-releasing factor induced adrenocorticortropic hormone release in the sheep fetus: blockade by cortisolAm J Obstet Gynecol. 1128.
1984 Cortisol infusion blocks adrenocorticortropic hormone but not vasopressin responses to hypotension in fetal lambsAm J Obstet Gynecol. 317.
1983 A vasopressin antagonist block norepinephrine and epinephrine responses to hemorrhage in the fetusEndocrinol. 2314.
1983 Vasopressin is important for restoring cardiovascular homeostasis in fetal lambs subjected to hemorrhageAm J Obstet Gynecol. 807.

Research Overview

  • Cardiovascular Physiology and Pharmacology
  • Expertise Keywords

  • Research : Use of Platelet Gel for the treatment of Cardiac Ischemia and Reperfusion Injury
  • Education And Training

  • B.S., Hampton University
  • Ph.D. in Physiology/Pharmacology, Bowman Gray School Of Medicine, Wake Forest University 1985
  • Full Name

  • Barbara Hargrave