Selected Publications

Articles In Academic Journals

Year Title
2014 Heat shock protein 90 inhibitors prevent LPS-induced endothelial barrier dysfunction by disrupting RhoA signaling.American Journal of Respiratory Cell and Molecular Biology. 170-9.
2014 Lipopolysaccharide-induced lung injury involves the nitration-mediated activation of RhoA.The Journal of biological chemistry. 4710-22.
2013 LPS induces pp60c-src-mediated tyrosine phosphorylation of Hsp90 in lung vascular endothelial cells and mouse lung.American journal of physiology. Lung cellular and molecular physiology. L883-93.
2012 Regulation of asthmatic airway relaxation by estrogen and heat shock protein 90.Journal of cellular physiology. 3036-43.
2010 Harvesting, identification and barrier function of human lung microvascular endothelial cells.Vascular pharmacology. 175-81.
2010 Mechanisms of nitric oxide synthase uncoupling in endotoxin-induced acute lung injury: role of asymmetric dimethylarginine.Vascular pharmacology. 182-90.
2010 The lectin-like domain of TNF protects from listeriolysin-induced hyperpermeability in human pulmonary microvascular endothelial cells - a crucial role for protein kinase C-alpha inhibition.Vascular pharmacology. 207-13.
2009 Effect of PPARgamma inhibition on pulmonary endothelial cell gene expression: gene profiling in pulmonary hypertension.Physiological genomics. 48-60.
2009 Estrogen replacement therapy prevents airway dysfunction in a murine model of allergen-induced asthma.Lung. 116-27.
2008 Heat shock protein 90 inhibitors attenuate LPS-induced endothelial hyperpermeability.American journal of physiology. Lung cellular and molecular physiology. L755-63.
2008 Heat shock protein 90 inhibitors protect and restore pulmonary endothelial barrier function.American Journal of Respiratory Cell and Molecular Biology. 551-9.
2007 Chaperone-dependent E3 ligase CHIP ubiquitinates and mediates proteasomal degradation of soluble guanylyl cyclase.American journal of physiology. Heart and circulatory physiology. H3080-7.
2007 Heat shock protein 90 inhibitors prolong survival, attenuate inflammation, and reduce lung injury in murine sepsis.American journal of respiratory and critical care medicine. 667-75.
2007 The green tea polyphenol epigallocatechin-3-gallate improves systemic hemodynamics and survival in rodent models of polymicrobial sepsis.Shock (Augusta, Ga.). 353-9.
2003 Novel complexes of guanylate cyclase with heat shock protein 90 and nitric oxide synthase.American journal of physiology. Heart and circulatory physiology. H669-78.
2002 Endothelium-independent effect of estrogen on Ca(2+)-activated K(+) channels in human coronary artery smooth muscle cells.Cardiovascular research. 650-61.
2002 Molecular mechanisms of iNOS induction by IL-1 beta and IFN-gamma in rat aortic smooth muscle cells.American journal of physiology. Cell physiology. C144-52.
2001 Nitric oxide differentially regulates induction of type II nitric oxide synthase in rat vascular smooth muscle cells versus macrophages.Arteriosclerosis, thrombosis, and vascular biology. 529-35.
2000 A reverse nuclear factor-kappaB element in the rat type II nitric oxide synthase promoter mediates the induction by interleukin-1beta and interferon-gamma in rat aortic smooth muscle cells.General pharmacology. 9-16.
2000 Non-NF-kappaB elements are required for full induction of the rat type II nitric oxide synthase in vascular smooth muscle cells.British journal of pharmacology. 270-8.
1998 Molecular cloning and analysis of the rat inducible nitric oxide synthase gene promoter in aortic smooth muscle cells.Biochemical pharmacology. 1873-80.