Selected Publications

Articles In Academic Journals

Year Title
2015 Histone deacetylase inhibitors prevent pulmonary endothelial hyperpermeability and acute lung injury by regulating heat shock protein 90 function.American journal of physiology. Lung cellular and molecular physiology. L1410-9.
2015 p53 protects against LPS-induced lung endothelial barrier dysfunction.American journal of physiology. Lung cellular and molecular physiology. L776-87.
2014 Dimethylarginine dimethylaminohydrolase II overexpression attenuates LPS-mediated lung leak in acute lung injury.American Journal of Respiratory Cell and Molecular Biology. 614-25.
2014 Heat shock protein 90 inhibitors prevent LPS-induced endothelial barrier dysfunction by disrupting RhoA signaling.American Journal of Respiratory Cell and Molecular Biology. 170-9.
2014 Lipopolysaccharide-induced lung injury involves the nitration-mediated activation of RhoA.The Journal of biological chemistry. 4710-22.
2014 NADPH oxidase 4 is expressed in pulmonary artery adventitia and contributes to hypertensive vascular remodeling.Arteriosclerosis, thrombosis, and vascular biology. 1704-15.
2014 Novel mechanism of attenuation of LPS-induced NF-?B activation by the heat shock protein 90 inhibitor, 17-N-allylamino-17-demethoxygeldanamycin, in human lung microvascular endothelial cells.American Journal of Respiratory Cell and Molecular Biology. 942-52.
2013 LPS induces pp60c-src-mediated tyrosine phosphorylation of Hsp90 in lung vascular endothelial cells and mouse lung.American journal of physiology. Lung cellular and molecular physiology. L883-93.
2012 Opposing actions of heat shock protein 90 and 70 regulate nicotinamide adenine dinucleotide phosphate oxidase stability and reactive oxygen species production.Arteriosclerosis, thrombosis, and vascular biology. 2989-99.
2012 Regulation of asthmatic airway relaxation by estrogen and heat shock protein 90.Journal of cellular physiology. 3036-43.
2010 Harvesting, identification and barrier function of human lung microvascular endothelial cells.Vascular pharmacology. 175-81.
2009 Estrogen replacement therapy prevents airway dysfunction in a murine model of allergen-induced asthma.Lung. 116-27.
2007 Chaperone-dependent E3 ligase CHIP ubiquitinates and mediates proteasomal degradation of soluble guanylyl cyclase.American journal of physiology. Heart and circulatory physiology. H3080-7.
2007 Estrogen as a new therapeutic target for asthma and chronic obstructive pulmonary disease.Drug news & perspectives. 241-52.
2007 Functional significance of hsp90 complexes with NOS and sGC in endothelial cells.Clinical hemorheology and microcirculation. 19-35.
2007 Heat shock protein 90 inhibitors prolong survival, attenuate inflammation, and reduce lung injury in murine sepsis.American journal of respiratory and critical care medicine. 667-75.
2007 Nitric oxide preconditioning regulates endothelial monolayer integrity via the heat shock protein 90-soluble guanylate cyclase pathway.American journal of physiology. Heart and circulatory physiology. H893-903.
2006 Angiotensin, bradykinin and the endothelium.Handbook of experimental pharmacology. 255-94.
2006 Effects of hsp90 binding inhibitors on sGC-mediated vascular relaxation.American journal of physiology. Heart and circulatory physiology. H260-8.
2005 Estrogen reduces carbachol-induced constriction of asthmatic airways by stimulating large-conductance voltage and calcium-dependent potassium channels.American Journal of Respiratory Cell and Molecular Biology. 239-47.
2003 Novel complexes of guanylate cyclase with heat shock protein 90 and nitric oxide synthase.American journal of physiology. Heart and circulatory physiology. H669-78.
2002 Endothelium-independent effect of estrogen on Ca(2+)-activated K(+) channels in human coronary artery smooth muscle cells.Cardiovascular Research. 650-61.
2001 Angiotensin II relaxes microvessels via the AT(2) receptor and Ca(2+)-activated K(+) (BK(Ca)) channels.Hypertension. 301-7.